Mesoporous silica nanoparticles as controlled release drug delivery and gene transfection carriers

…, JL Vivero-Escoto, CW Wu, VSY Lin - Advanced drug delivery …, 2008 - Elsevier
In this review, we highlight the recent research developments of a series of surface-functionalized
mesoporous silica nanoparticle (MSN) materials as efficient drug delivery carriers. The …

A mesoporous silica nanosphere-based carrier system with chemically removable CdS nanoparticle caps for stimuli-responsive controlled release of …

…, K Jeftinija, S Xu, S Jeftinija, VSY Lin - Journal of the …, 2003 - ACS Publications
An MCM-41 type mesoporous silica nanosphere-based (MSN) controlled-release delivery
system has been synthesized and characterized using surface-derivatized cadmium sulfide (…

A porous silicon-based optical interferometric biosensor

VSY Lin, K Motesharei, KPS Dancil, MJ Sailor… - Science, 1997 - science.org
A biosensor has been developed based on induced wavelength shifts in the Fabry-Perot
fringes in the visible-light reflection spectrum of appropriately derivatized thin films of porous …

Myogenin, a factor regulating myogenesis, has a domain homologous to MyoD

WE Wright, DA Sassoon, VK Lin - Cell, 1989 - cell.com
In this report, we describe the isolation, sequence, and initial characterization of the cDNA
for the musclespecific regulatory factor skeletal myogenin. Transfection of myogenin into the …

Mesoporous silica nanoparticles deliver DNA and chemicals into plants

F Torney, BG Trewyn, VSY Lin, K Wang - Nature nanotechnology, 2007 - nature.com
Surface-functionalized silica nanoparticles can deliver DNA 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 and drugs
9 , 10 , 11 , 12 , 13 , 14 , 15 into animal cells and tissues. However, their use in plants is …

Synthesis and functionalization of a mesoporous silica nanoparticle based on the sol–gel process and applications in controlled release

…, II Slowing, S Giri, HT Chen, VSY Lin - Accounts of chemical …, 2007 - ACS Publications
Victor Lin. His research centers on biological applications of MSNs. … candidate in Victor
Lin’s research group in the Department of Chemistry at Iowa State University. His research …

Mesoporous silica nanoparticles for intracellular controlled drug delivery

JL Vivero‐Escoto, II Slowing, BG Trewyn, VSY Lin - Small, 2010 - Wiley Online Library
The application of nanotechnology in the field of drug delivery has attracted much attention
in the latest decades. Recent breakthroughs on the morphology control and surface …

Effect of surface functionalization of MCM-41-type mesoporous silica nanoparticles on the endocytosis by human cancer cells

I Slowing, BG Trewyn, VSY Lin - Journal of the American Chemical …, 2006 - ACS Publications
We have synthesized a series of MCM-41-type mesoporous silica nanoparticles (MSN). The
surface of the MSNs are functionalized with 3-aminopropyl (AP), 3-guanidinopropyl (GP), 3-[…

A polyamidoamine dendrimer-capped mesoporous silica nanosphere-based gene transfection reagent

…, K Jeftinija, EW Rowe, S Jeftinija, VSY Lin - Journal of the …, 2004 - ACS Publications
We synthesized a MCM-41-type mesoporous silica nanosphere (MSN)-based gene transfection
system, where second generation (G2) polyamidoamines (PAMAMs) were covalently …

Highly conjugated, acetylenyl bridged porphyrins: new models for light-harvesting antenna systems

VSY Lin, SG DiMagno, MJ Therien - Science, 1994 - science.org
A new class of porphyrin-based chromophore systems has been prepared from ethyne-elaborated
porphyrin synthons through the use of metal-mediated cross-coupling methodologies. …