[HTML][HTML] Scalable and accurate deep learning with electronic health records
Predictive modeling with electronic health record (EHR) data is anticipated to drive personalized
medicine and improve healthcare quality. Constructing predictive statistical models …
medicine and improve healthcare quality. Constructing predictive statistical models …
[HTML][HTML] New insights into atopic dermatitis
…, M Boguniewicz, MD Howell… - The Journal of …, 2004 - Am Soc Clin Investig
Atopic dermatitis is a chronic inflammatory skin disease associated with cutaneous hyperreactivity
to environmental triggers and is often the first step in the atopic march that results in …
to environmental triggers and is often the first step in the atopic march that results in …
Cytokine modulation of atopic dermatitis filaggrin skin expression
BACKGROUND: Atopic dermatitis (AD) is a chronic inflammatory skin disease that is
characterized by a defective skin barrier function. Recent studies have reported mutations of the …
characterized by a defective skin barrier function. Recent studies have reported mutations of the …
Neutralising antibody activity against SARS-CoV-2 VOCs B. 1.617. 2 and B. 1.351 by BNT162b2 vaccination
that emerged in the UK with the second COVID-19 wave in late 2020. The efficacy of currently
licensed COVID-19 vaccines against B. 1.617. 2 is unknown; although it possesses 12 …
licensed COVID-19 vaccines against B. 1.617. 2 is unknown; although it possesses 12 …
Cytokine milieu of atopic dermatitis, as compared to psoriasis, skin prevents induction of innate immune response genes
Atopic dermatitis (AD) and psoriasis are the two most common chronic skin diseases. However
patients with AD, but not psoriasis, suffer from frequent skin infections. To understand the …
patients with AD, but not psoriasis, suffer from frequent skin infections. To understand the …
Serum lactate as a predictor of mortality in emergency department patients with infection
STUDY OBJECTIVE: Little is known about risk-stratification biomarkers in emergency department
(ED) patients with suspected infection, and lactate is a biologically plausible candidate. …
(ED) patients with suspected infection, and lactate is a biologically plausible candidate. …
[PDF][PDF] Acetyl-CoA synthetase 2 promotes acetate utilization and maintains cancer cell growth under metabolic stress
…, E Shanks, G Kalna, RE Saunders, M Jiang, M Howell… - Cancer cell, 2015 - cell.com
A functional genomics study revealed that the activity of acetyl-CoA synthetase 2 (ACSS2)
contributes to cancer cell growth under low-oxygen and lipid-depleted conditions. …
contributes to cancer cell growth under low-oxygen and lipid-depleted conditions. …
Strategies to prevent ventilator-associated pneumonia in acute care hospitals: 2014 update
…, EC Eichenwald, LR Greene, MD Howell… - Infection Control & …, 2014 - cambridge.org
Previously published guidelines are available that provide comprehensive recommendations
for detecting and preventing healthcare-associated infections (HAIs). The intent of this …
for detecting and preventing healthcare-associated infections (HAIs). The intent of this …
Replication stress links structural and numerical cancer chromosomal instability
Cancer chromosomal instability (CIN) results in an increased rate of change of chromosome
number and structure and generates intratumour heterogeneity 1 , 2 . CIN is observed in …
number and structure and generates intratumour heterogeneity 1 , 2 . CIN is observed in …
Iatrogenic gastric acid suppression and the risk of nosocomial Clostridium difficile infection
MD Howell, V Novack, P Grgurich… - Archives of internal …, 2010 - jamanetwork.com
Background The incidence and severity ofClostridium difficileinfections are increasing. Acid-suppressive
therapy has been suggested as a risk factor forC difficile,but this remains …
therapy has been suggested as a risk factor forC difficile,but this remains …