The bioequivalence problem is of practical importance because the approval of most generic
drugs in the United States and the European Community (EC) requires the establishment …

In this paper, we show that under a fairly innocuous assumption on price inefficiency, market
capitalization weighted portfolios are sub-optimal. If market prices are more volatile than is …

For comparing k treatment effects θ 1 , θ 2 , ⋯ θ k , often the parameters of primary interest
are θ i - max j≠ i θ j , i = 1, ⋯, k. In this article, we develop constrained 100P * % two-sided …

Dear Editor, The pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) highlights the need to develop effective …

Background Weight loss may improve glucose control in persons with type 2 diabetes. The
effects of fat quality, as opposed to quantity, on weight loss are not well understood. Objective …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) leads to shutoff of protein
synthesis, and nsp1, a central shutoff factor in coronaviruses, inhibits cellular mRNA …

The COVID‐19 pathogen, SARS‐CoV‐2, requires its main protease (SC2M Pro ) to digest
two of its translated long polypeptides to form a number of mature proteins that are essential …

Guided by a computational docking analysis, about 30 Food and Drug Administration/European
Medicines Agency (FDA/EMA)-approved small-molecule medicines were characterized …

Not all simultaneous inferences need multiplicity adjustment. If the sequence of individual
inferences is predefined, and failure to achieve the desired inference at any step renders …

purpose. The purpose of this study was to identify reliable predictors of the onset of juvenile
myopia. methods. The data from 554 children enrolled in the Orinda Longitudinal Study of …