User profiles for J. Youn

Ji-Young Youn

- Verified email at sickkids.ca - Cited by 3391

Jiun Youn

- Verified email at vuw.ac.nz - Cited by 925

The biology of myeloid‐derived suppressor cells: the blessing and the curse of morphological and functional heterogeneity

JI Youn, DI Gabrilovich - European journal of immunology, 2010 - Wiley Online Library
Myeloid‐derived suppressor cells (MDSC) play an important role in the cellular network
regulating immune responses in cancer, chronic infectious diseases, autoimmunity, and in other …

Rodent models in neuroscience research: is it a rat race?

B Ellenbroek, J Youn - Disease models & mechanisms, 2016 - journals.biologists.com
Rodents (especially Mus musculus and Rattus norvegicus) have been the most widely used
models in biomedical research for many years. A notable shift has taken place over the last …

Traditional Chinese Medicine (TCM) in the treatment of COVID-19 and other viral infections: Efficacies and mechanisms

K Huang, P Zhang, Z Zhang, JY Youn, C Wang… - Pharmacology & …, 2021 - Elsevier
COVID-19 has remained an uncontained, worldwide pandemic. While battling for the
disease in China, six Traditional Chinese Medicine (TCM) recipes have been shown to be …

Subsets of myeloid-derived suppressor cells in tumor-bearing mice

JI Youn, S Nagaraj, M Collazo… - The Journal of …, 2008 - journals.aai.org
Myeloid-derived suppressor cells (MDSC) are a heterogeneous group of cells that play a
critical role in tumor associated immune suppression. In an attempt to identify a specific subset …

HIF-1α regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment

…, T Condamine, L Lu, MJ Cotter, JI Youn… - Journal of Experimental …, 2010 - rupress.org
Myeloid-derived suppressor cells (MDSCs) are a major component of the immune-suppressive
network described in cancer and many other pathological conditions. We demonstrate …

Influence of dispersion states of carbon nanotubes on physical properties of epoxy nanocomposites

YS Song, JR Youn - Carbon, 2005 - Elsevier
Effects of different dispersion states of carbon nanotubes (CNTs) on rheological, mechanical,
electrical, and thermal properties of the epoxy nanocomposites were studied. The …

A proximity-dependent biotinylation map of a human cell

…, B Rathod, GG Hesketh, KT Abe, JY Youn… - Nature, 2021 - nature.com
Compartmentalization is a defining characteristic of eukaryotic cells, and partitions distinct
biochemical processes into discrete subcellular locations. Microscopy 1 and biochemical …

Anti-obesity effects of α-lipoic acid mediated by suppression of hypothalamic AMP-activated protein kinase

…, J Ha, IS Park, IK Lee, B Viollet, JH Youn… - Nature medicine, 2004 - nature.com
AMP-activated protein kinase (AMPK) functions as a fuel sensor in the cell and is activated
when cellular energy is depleted. Here we report that α-lipoic acid (α-LA), a cofactor of …

Effects of surface modification on rheological and mechanical properties of CNT/epoxy composites

JA Kim, DG Seong, TJ Kang, JR Youn - Carbon, 2006 - Elsevier
Despite superior properties of carbon nanotubes (CNTs), physical properties of the CNT/epoxy
composites are not improved significantly because interfacial bonding between the CNTs …

[PDF][PDF] High-density proximity mapping reveals the subcellular organization of mRNA-associated granules and bodies

JY Youn, WH Dunham, SJ Hong, JDR Knight… - Molecular cell, 2018 - cell.com
Youn et al. performed proximity-based proteomics on 119 human proteins involved in the …
Vidal for the ANKRD17 and UNK constructs; J. Pelletier for eIF4A inhibitors and the DDX3X …