It is time to end all forms of stigma and discrimination against people with mental health
conditions, for whom there is double jeopardy: the impact of the primary condition and the severe …

A good night's sleep is one of life's most satisfying experiences, while sleeplessness is stressful
and causes cognitive impairment. Yet the mechanisms that regulate the ability to sleep …

Non-alcoholic fatty liver disease (NAFLD) is considered the most common liver disorder,
affecting around 25% of the population worldwide. It is a complex disease spectrum, closely …

A new approach to ECG arrhythmia analysis is described. It is based on hidden Markov
modeling (HMM), a technique successfully used since the mid 1970s to model speech …

… Adult male Sprague-Dawley rats (Zivic-Miller Laboratories, Zelienople, PA) weighing 275–350
g were used in this study. Animals were maintained in a standardized environment under …

Sleep architecture is often disturbed after a stressful event; nevertheless, little is known about
the brain circuitry responsible for the sleep perturbations induced by stress. We exposed …

… Rats were anesthetized initially with 3% isoflurane in 100% O 2 and transitioned to urethane
(0.8 g/kg) and chloralose (80 mg/kg) following cannulation of a femoral artery and vein. …

… a subset of rats included in this study has been previously published (Cano et al., 2000). …
G shows the rostral part of LC (DBH-IR, noninfected), infected neurons in BN (PRV-IR), and …

… Adult male Sprague–Dawley rats (n = 18; weight 275–325 g) from Harlan were housed
individually under a 12-hour light/dark cycle (lights on at 7:00 AM) at 22C, with ad libitum access …

… Cano-Saper Model The Cano-Saper model suggests that insomnia represents a hybrid
state, one that is, from a neurobiological perspective, part wake and part sleep. One implication …