Primary care physicians' attitudes about obesity and its treatment

…, RS Sanderson, DB Allison, A Kessler - Obesity …, 2003 - Wiley Online Library
Objective: This study was designed to assess physicians’ attitudes toward obese patients and
the causes and treatment of obesity. Research Methods and Procedures: A questionnaire …

Phantoms never die: living with unreliable population data

…, D Blake, K Dowd, AR Kessler - Journal of the Royal …, 2016 - academic.oup.com
The analysis of national mortality trends is critically dependent on the quality of the population,
exposures and deaths data that underpin death rates. We develop a framework that …

Still living with mortality: The longevity risk transfer market after one decade

D Blake, AJG Cairns, K Dowd, AR Kessler - British Actuarial Journal, 2019 - cambridge.org
This paper updates Living with Mortality published in 2006. It describes how the longevity
risk transfer market has developed over the intervening period, and, in particular, how …

The impact of COVID-19 on future higher-age mortality

…, DP Blake, A Kessler, M Kessler - Available at SSRN …, 2020 - papers.ssrn.com
This paper seeks to assess the potential longer-term impact of the COVID-19 pandemic on
those who survive. We propose a simple model for accelerated deaths that draws on the …

[PDF][PDF] Hepatitis E virus infection activates NOD‐like receptor family pyrin domain‐containing 3 inflammasome antagonizing interferon response but therapeutically …

Y Li, P Yu, AL Kessler, J Shu, X Liu, Z Liang, J Liu… - …, 2022 - Wiley Online Library
Background and Aims HEV infection is the most common cause of liver inflammation, but the
pathogenic mechanisms remain largely unclear. We aim to explore whether HEV infection …

New solutions to an age-old problem: innovative strategies for managing pension and longevity risk

A Kessler - North American Actuarial Journal, 2021 - Taylor & Francis
The recent wave of innovation in the pension and longevity risk transfer market is barely a
decade old, but more than US $470 billion in global transaction activity has taken place, …

[HTML][HTML] Induction of broad multifunctional CD8+ and CD4+ T cells by hepatitis B virus antigen-based synthetic long peptides ex vivo

…, K Kwappenberg, AS Wiekmeijer, AL Kessler… - Frontiers in …, 2023 - frontiersin.org
Introduction Therapeutic vaccination based on synthetic long peptides (SLP ® ) containing
both CD4+ and CD8+ T cell epitopes is a promising treatment strategy for chronic hepatitis B …

[HTML][HTML] The potential of soluble human leukocyte antigen molecules for early cancer detection and therapeutic vaccine design

AL Kessler, MJ Bruno, SI Buschow - Vaccines, 2020 - mdpi.com
Human leukocyte antigen (HLA) molecules are essential for anti-tumor immunity, as they
display tumor-derived peptides to drive tumor eradication by cytotoxic T lymphocytes. HLA …

[PDF][PDF] Introductions

A Kessler, C Jurado, ML Delgado, C Meléndez… - 2023 - climateactionreserve.org
Amy KesslerAmy Kessler: akessler@climateactionreserve.org Miguel Delgado:
mdelgado@climateactionreserve.org Claudia Jurado: cjurado@climateactionreserve.org …

[HTML][HTML] Empirical evaluation of the use of computational HLA binding as an early filter to the mass spectrometry-based epitope discovery workflow

…, MTA de Beijer, RJ Luijten, K Bezstarosti, AL Kessler… - Cancers, 2021 - mdpi.com
Simple Summary Many different human leukocyte antigen (HLA)-types exist across the
population that each binds a specific motif of amino acids. HLA-peptide complexes are the …